The Pennsylvania STEM Initiative is a statewide effort within the Commonwealth of Pennsylvania, designed to create the the foundation for the state’s future competitiveness by establishing a network of partners and programs that support the development and deployment of science, technology, engineering and mathematics education and workforce development.

Established in August 2007, the Pennsylvania STEM Initiative is an initiative of the National Governor's Association and the Team Pennsylvania Foundation with the support of leaders from multiple Commonwealth agencies as well as business, secondary education and higher education partners.As a result of this partnership, the NGA Center for Best Practices awarded Pennsylvania one of six statewide STEM grants to fund the initial two years of the STEM effort.

The Pennsylvania STEM Initiative is a key component in a nationwide strategy for implementing a STEM education redesign throughout the nation.  This national effort is being conducted through the leadership of the National Governor's Association.